Age-dependent VDR peak DNA methylation as a mechanism for latitude-dependent multiple sclerosis risk

BACKGROUND: The mechanisms linking UV radiation and vitamin D exposure to the risk of acquiring the latitude and critical period-dependent autoimmune disease, multiple sclerosis, is unclear. We examined the effect of vitamin D on DNA methylation and DNA methylation at vitamin D receptor binding site...

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Detalles Bibliográficos
Autores principales: Ong, Lawrence T. C., Schibeci, Stephen D., Fewings, Nicole L., Booth, David R., Parnell, Grant P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863270/
https://www.ncbi.nlm.nih.gov/pubmed/33541415
http://dx.doi.org/10.1186/s13072-021-00383-x

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