Genetic Contributions to Acquired Epilepsies

Whether genetic factors contribute to acquired epilepsies has long been controversial. Supporters observe that, among individuals exposed to seemingly the same brain insult, only a minority develops unprovoked seizures. Yet, only in relatively recent years have studies started to build a case for ge...

Descripción completa

Detalles Bibliográficos
Autores principales: Perucca, Piero, Scheffer, Ingrid E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Current Review in Clinical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863311/
https://www.ncbi.nlm.nih.gov/pubmed/32990457
http://dx.doi.org/10.1177/1535759720954254
_version_ 1783647467482382336
author Perucca, Piero
Scheffer, Ingrid E.
author_facet Perucca, Piero
Scheffer, Ingrid E.
author_sort Perucca, Piero
collection PubMed
description Whether genetic factors contribute to acquired epilepsies has long been controversial. Supporters observe that, among individuals exposed to seemingly the same brain insult, only a minority develops unprovoked seizures. Yet, only in relatively recent years have studies started to build a case for genetic contributions. Here, we appraise this emerging evidence, by providing a critical review of studies published in the field.
format Online
Article
Text
id pubmed-7863311
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher SAGE Publications
record_format MEDLINE/PubMed
spelling pubmed-78633112021-02-16 Genetic Contributions to Acquired Epilepsies Perucca, Piero Scheffer, Ingrid E. Epilepsy Curr Current Review in Clinical Science Whether genetic factors contribute to acquired epilepsies has long been controversial. Supporters observe that, among individuals exposed to seemingly the same brain insult, only a minority develops unprovoked seizures. Yet, only in relatively recent years have studies started to build a case for genetic contributions. Here, we appraise this emerging evidence, by providing a critical review of studies published in the field. SAGE Publications 2020-09-29 /pmc/articles/PMC7863311/ /pubmed/32990457 http://dx.doi.org/10.1177/1535759720954254 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc-nd/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License (https://creativecommons.org/licenses/by-nc-nd/4.0/) which permits non-commercial use, reproduction and distribution of the work as published without adaptation or alteration, without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Current Review in Clinical Science
Perucca, Piero
Scheffer, Ingrid E.
Genetic Contributions to Acquired Epilepsies
title Genetic Contributions to Acquired Epilepsies
title_full Genetic Contributions to Acquired Epilepsies
title_fullStr Genetic Contributions to Acquired Epilepsies
title_full_unstemmed Genetic Contributions to Acquired Epilepsies
title_short Genetic Contributions to Acquired Epilepsies
title_sort genetic contributions to acquired epilepsies
topic Current Review in Clinical Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863311/
https://www.ncbi.nlm.nih.gov/pubmed/32990457
http://dx.doi.org/10.1177/1535759720954254
work_keys_str_mv AT peruccapiero geneticcontributionstoacquiredepilepsies
AT schefferingride geneticcontributionstoacquiredepilepsies

Ejemplares similares