Mismatch repair deficiency is associated with specific morphologic features and frequent loss of ARID1A expression in ovarian clear cell carcinoma

BACKGROUND: Ovarian clear cell carcinoma (OCCC) is the second subtype of ovarian epithelial carcinoma reported to be closely related to Lynch syndrome (LS). ARID1A mutation is an important pathogenetic mechanism in OCCC that leads to loss of ARID1A expression in approximately half of OCCCs. However,...

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Detalles Bibliográficos
Autores principales: Ge, Huijuan, Xiao, Yaoxin, Qin, Guangqi, Gu, Yanzi, Cai, Xu, Jiang, Wenhua, Tu, Xiaoyu, Yang, Wentao, Bi, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863332/
https://www.ncbi.nlm.nih.gov/pubmed/33541386
http://dx.doi.org/10.1186/s13000-021-01071-w

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