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Sirtuin 3 protects against anesthesia/surgery-induced cognitive decline in aged mice by suppressing hippocampal neuroinflammation

BACKGROUND: Postoperative cognitive dysfunction (POCD) is a very common complication that might increase the morbidity and mortality of elderly patients after surgery. However, the mechanism of POCD remains largely unknown. The NAD-dependent deacetylase protein Sirtuin 3 (SIRT3) is located in the mi...

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Detalles Bibliográficos
Autores principales:	Liu, Qiang, Sun, Yi-Man, Huang, Hui, Chen, Chen, Wan, Jie, Ma, Lin-Hui, Sun, Yin-Ying, Miao, Hui-Hui, Wu, Yu-Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863360/ https://www.ncbi.nlm.nih.gov/pubmed/33541361 http://dx.doi.org/10.1186/s12974-021-02089-z

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