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Effects of SP600125 and hypothermic machine perfusion on livers donated after cardiac death in a pig allograft transplantation model

BACKGROUND: Hypothermic machine perfusion (HMP) improves the quality of donor livers for transplantation, both in animal models and in clinical practice. Treatment with SP600125, an inhibitor of c-Jun N-terminal kinase (JNK), can suppress the JNK signaling pathway to alleviate donor liver ischemia–r...

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Detalles Bibliográficos
Autores principales:	Zhang, Yijie, Pan, Qi, Cheng, Ying, Liu, Yongfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863371/ https://www.ncbi.nlm.nih.gov/pubmed/33546770 http://dx.doi.org/10.1186/s40001-020-00472-9

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