Cargando…

Testosterone activates glucose metabolism through AMPK and androgen signaling in cardiomyocyte hypertrophy

BACKGROUND: Testosterone regulates nutrient and energy balance to maintain protein synthesis and metabolism in cardiomyocytes, but supraphysiological concentrations induce cardiac hypertrophy. Previously, we determined that testosterone increased glucose uptake—via AMP-activated protein kinase (AMPK...

Descripción completa

Detalles Bibliográficos
Autores principales: Troncoso, Mayarling Francisca, Pavez, Mario, Wilson, Carlos, Lagos, Daniel, Duran, Javier, Ramos, Sebastián, Barrientos, Genaro, Silva, Patricio, Llanos, Paola, Basualto-Alarcón, Carla, Westenbrink, B. Daan, Lavandero, Sergio, Estrada, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863443/
https://www.ncbi.nlm.nih.gov/pubmed/33546773
http://dx.doi.org/10.1186/s40659-021-00328-4