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Clinical outcomes of postoperative extracorporeal membrane oxygenation support in Stanford type a aortic dissection

BACKGROUND: Extracorporeal membrane oxygenation (ECMO) support may be considered to reduce mortality but survival and clinical outcomes are uncertain after Stanford type A Aortic dissection (TAAD). We analyzed the data of TAAD patients with postoperative ECMO support in our institution to investigat...

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Autores principales: Fan, Fudong, Zhou, Qing, Pan, Jun, Cao, Hailong, Li, Kai, Xue, Yunxing, Ge, Min, Luo, Xuan, Chen, Yang, Wang, Dongjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863498/
https://www.ncbi.nlm.nih.gov/pubmed/33546609
http://dx.doi.org/10.1186/s12871-021-01252-6
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author Fan, Fudong
Zhou, Qing
Pan, Jun
Cao, Hailong
Li, Kai
Xue, Yunxing
Ge, Min
Luo, Xuan
Chen, Yang
Wang, Dongjin
author_facet Fan, Fudong
Zhou, Qing
Pan, Jun
Cao, Hailong
Li, Kai
Xue, Yunxing
Ge, Min
Luo, Xuan
Chen, Yang
Wang, Dongjin
author_sort Fan, Fudong
collection PubMed
description BACKGROUND: Extracorporeal membrane oxygenation (ECMO) support may be considered to reduce mortality but survival and clinical outcomes are uncertain after Stanford type A Aortic dissection (TAAD). We analyzed the data of TAAD patients with postoperative ECMO support in our institution to investigate clinical outcomes. METHODS: In this retrospective cohort study, all clinical data of TAAD patients with postoperative ECMO support from January 2013 to October 2019 in our institution were harvested. Cases with redo or incomplete records were excluded. RESULTS: 22 cases were enrolled, 18 male and 4 female. The mean age was52.85±10.91 years. 20 patients underwent VA-ECMO treatment and 2 patients received VV-ECMO support. The support time was92.54±78.71 hours. 9 patients were successfully weaned from ECMO. 30-day in-hospital survival rate was 27.27 % (6/22). The follow-up duration is from 5 to 74 months. The median follow-up time is 35 months. Only four patients were still alive at the end of the follow-up period. CONCLUSIONS: The mortality of TAAD patients with postoperativesevere circulatory and respiratory dysfunctions is high. ECMO would be considered as a valuable contribution to save lives. But more experience needs to be accumulated to improve clinical outcome.
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spelling pubmed-78634982021-02-05 Clinical outcomes of postoperative extracorporeal membrane oxygenation support in Stanford type a aortic dissection Fan, Fudong Zhou, Qing Pan, Jun Cao, Hailong Li, Kai Xue, Yunxing Ge, Min Luo, Xuan Chen, Yang Wang, Dongjin BMC Anesthesiol Research Article BACKGROUND: Extracorporeal membrane oxygenation (ECMO) support may be considered to reduce mortality but survival and clinical outcomes are uncertain after Stanford type A Aortic dissection (TAAD). We analyzed the data of TAAD patients with postoperative ECMO support in our institution to investigate clinical outcomes. METHODS: In this retrospective cohort study, all clinical data of TAAD patients with postoperative ECMO support from January 2013 to October 2019 in our institution were harvested. Cases with redo or incomplete records were excluded. RESULTS: 22 cases were enrolled, 18 male and 4 female. The mean age was52.85±10.91 years. 20 patients underwent VA-ECMO treatment and 2 patients received VV-ECMO support. The support time was92.54±78.71 hours. 9 patients were successfully weaned from ECMO. 30-day in-hospital survival rate was 27.27 % (6/22). The follow-up duration is from 5 to 74 months. The median follow-up time is 35 months. Only four patients were still alive at the end of the follow-up period. CONCLUSIONS: The mortality of TAAD patients with postoperativesevere circulatory and respiratory dysfunctions is high. ECMO would be considered as a valuable contribution to save lives. But more experience needs to be accumulated to improve clinical outcome. BioMed Central 2021-02-05 /pmc/articles/PMC7863498/ /pubmed/33546609 http://dx.doi.org/10.1186/s12871-021-01252-6 Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Fan, Fudong
Zhou, Qing
Pan, Jun
Cao, Hailong
Li, Kai
Xue, Yunxing
Ge, Min
Luo, Xuan
Chen, Yang
Wang, Dongjin
Clinical outcomes of postoperative extracorporeal membrane oxygenation support in Stanford type a aortic dissection
title Clinical outcomes of postoperative extracorporeal membrane oxygenation support in Stanford type a aortic dissection
title_full Clinical outcomes of postoperative extracorporeal membrane oxygenation support in Stanford type a aortic dissection
title_fullStr Clinical outcomes of postoperative extracorporeal membrane oxygenation support in Stanford type a aortic dissection
title_full_unstemmed Clinical outcomes of postoperative extracorporeal membrane oxygenation support in Stanford type a aortic dissection
title_short Clinical outcomes of postoperative extracorporeal membrane oxygenation support in Stanford type a aortic dissection
title_sort clinical outcomes of postoperative extracorporeal membrane oxygenation support in stanford type a aortic dissection
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863498/
https://www.ncbi.nlm.nih.gov/pubmed/33546609
http://dx.doi.org/10.1186/s12871-021-01252-6
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