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Complications of dual growing rod with all-pedicle screw instrumentation in the treatment of early-onset scoliosis

BACKGROUND: Treatment of early-onset scoliosis (EOS) is still a challenge to patients, families, and surgeons. Previous studies have indicated that EOS patients are at high risk for complications following growth-friendly surgery. This study was performed to evaluate the results and complications of...

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Autores principales: Zarei, Mohammad, Tavakoli, Mehdi, Ghadimi, Ehsan, Moharrami, Alireza, Nili, Ali, Vafaei, Ali, Tamehri Zadeh, Seyed Saeed, Baghdadi, Soroush
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863499/
https://www.ncbi.nlm.nih.gov/pubmed/33546727
http://dx.doi.org/10.1186/s13018-021-02267-y
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author Zarei, Mohammad
Tavakoli, Mehdi
Ghadimi, Ehsan
Moharrami, Alireza
Nili, Ali
Vafaei, Ali
Tamehri Zadeh, Seyed Saeed
Baghdadi, Soroush
author_facet Zarei, Mohammad
Tavakoli, Mehdi
Ghadimi, Ehsan
Moharrami, Alireza
Nili, Ali
Vafaei, Ali
Tamehri Zadeh, Seyed Saeed
Baghdadi, Soroush
author_sort Zarei, Mohammad
collection PubMed
description BACKGROUND: Treatment of early-onset scoliosis (EOS) is still a challenge to patients, families, and surgeons. Previous studies have indicated that EOS patients are at high risk for complications following growth-friendly surgery. This study was performed to evaluate the results and complications of all-pedicle screw dual growing rod instrumentation in the treatment of EOS. METHODS: In an IRB-approved retrospective study, we searched the electronic medical records of our institution for all patients who underwent posterior spinal instrumentation for scoliosis between March 2014 and March 2017. Patients under the age of 10 at the time of surgery who were treated with a growth-friendly technique were then selected. Patients with incomplete records and less than 2 years of follow-up were excluded. Charts, operative notes, clinic visits, and radiographs were extracted. Radiographs were reviewed, and the main curve Cobb angle, thoracic kyphosis, pelvic tilt, pelvic incidence, sacral slope, and proximal junctional angles were measured. We specifically looked for any intra-operative or post-operative complications. Statistical analysis was performed to determine the risk factors of complications. RESULTS: A total of 42 patients with a mean age of 4.8 ± 2.1 years (range, 1.5–8 years) were included in the final analysis. Patients were followed for a median of 34 months (range, 24–55). The major curve was corrected from a mean of 42.9° ± 10.7° to 28.8° ± 9.6° at the latest follow-up. Proximal junctional angles and thoracic kyphosis increased significantly during the follow-up period (both P values < 0.001). A total of 7 complications (17%) were observed. Four patients (10%) developed superficial surgical site infections, all of which resolved with antibiotics and one round of surgical debridement. Three cases (7%) of proximal junctional kyphosis (PJK) were encountered during the study period, none of which required revision surgery. Pre-operative thoracic kyphosis was the only significant risk factor for the development of PJK. CONCLUSIONS: Our findings suggest that in settings without access to magnetically controlled growing rods, dual growing rods with all-pedicle screw instrumentation is still a viable treatment strategy with comparable results and complications. The most common complications are infection and PJK, with the latter being associated with a larger pre-operative thoracic kyphosis.
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spelling pubmed-78634992021-02-05 Complications of dual growing rod with all-pedicle screw instrumentation in the treatment of early-onset scoliosis Zarei, Mohammad Tavakoli, Mehdi Ghadimi, Ehsan Moharrami, Alireza Nili, Ali Vafaei, Ali Tamehri Zadeh, Seyed Saeed Baghdadi, Soroush J Orthop Surg Res Research Article BACKGROUND: Treatment of early-onset scoliosis (EOS) is still a challenge to patients, families, and surgeons. Previous studies have indicated that EOS patients are at high risk for complications following growth-friendly surgery. This study was performed to evaluate the results and complications of all-pedicle screw dual growing rod instrumentation in the treatment of EOS. METHODS: In an IRB-approved retrospective study, we searched the electronic medical records of our institution for all patients who underwent posterior spinal instrumentation for scoliosis between March 2014 and March 2017. Patients under the age of 10 at the time of surgery who were treated with a growth-friendly technique were then selected. Patients with incomplete records and less than 2 years of follow-up were excluded. Charts, operative notes, clinic visits, and radiographs were extracted. Radiographs were reviewed, and the main curve Cobb angle, thoracic kyphosis, pelvic tilt, pelvic incidence, sacral slope, and proximal junctional angles were measured. We specifically looked for any intra-operative or post-operative complications. Statistical analysis was performed to determine the risk factors of complications. RESULTS: A total of 42 patients with a mean age of 4.8 ± 2.1 years (range, 1.5–8 years) were included in the final analysis. Patients were followed for a median of 34 months (range, 24–55). The major curve was corrected from a mean of 42.9° ± 10.7° to 28.8° ± 9.6° at the latest follow-up. Proximal junctional angles and thoracic kyphosis increased significantly during the follow-up period (both P values < 0.001). A total of 7 complications (17%) were observed. Four patients (10%) developed superficial surgical site infections, all of which resolved with antibiotics and one round of surgical debridement. Three cases (7%) of proximal junctional kyphosis (PJK) were encountered during the study period, none of which required revision surgery. Pre-operative thoracic kyphosis was the only significant risk factor for the development of PJK. CONCLUSIONS: Our findings suggest that in settings without access to magnetically controlled growing rods, dual growing rods with all-pedicle screw instrumentation is still a viable treatment strategy with comparable results and complications. The most common complications are infection and PJK, with the latter being associated with a larger pre-operative thoracic kyphosis. BioMed Central 2021-02-05 /pmc/articles/PMC7863499/ /pubmed/33546727 http://dx.doi.org/10.1186/s13018-021-02267-y Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Zarei, Mohammad
Tavakoli, Mehdi
Ghadimi, Ehsan
Moharrami, Alireza
Nili, Ali
Vafaei, Ali
Tamehri Zadeh, Seyed Saeed
Baghdadi, Soroush
Complications of dual growing rod with all-pedicle screw instrumentation in the treatment of early-onset scoliosis
title Complications of dual growing rod with all-pedicle screw instrumentation in the treatment of early-onset scoliosis
title_full Complications of dual growing rod with all-pedicle screw instrumentation in the treatment of early-onset scoliosis
title_fullStr Complications of dual growing rod with all-pedicle screw instrumentation in the treatment of early-onset scoliosis
title_full_unstemmed Complications of dual growing rod with all-pedicle screw instrumentation in the treatment of early-onset scoliosis
title_short Complications of dual growing rod with all-pedicle screw instrumentation in the treatment of early-onset scoliosis
title_sort complications of dual growing rod with all-pedicle screw instrumentation in the treatment of early-onset scoliosis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863499/
https://www.ncbi.nlm.nih.gov/pubmed/33546727
http://dx.doi.org/10.1186/s13018-021-02267-y
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