Early maternal care restores LINE-1 methylation and enhances neurodevelopment in preterm infants

BACKGROUND: Preterm birth affects almost 9–11% of newborns and is one of the leading causes of childhood neurodevelopmental disabilities; the underlying molecular networks are poorly defined. In neurons, retrotransposons LINE-1 (L1) are an active source of genomic mosaicism that is deregulated in se...

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Detalles Bibliográficos
Autores principales: Fontana, Camilla, Marasca, Federica, Provitera, Livia, Mancinelli, Sara, Pesenti, Nicola, Sinha, Shruti, Passera, Sofia, Abrignani, Sergio, Mosca, Fabio, Lodato, Simona, Bodega, Beatrice, Fumagalli, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863536/
https://www.ncbi.nlm.nih.gov/pubmed/33541338
http://dx.doi.org/10.1186/s12916-020-01896-0

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