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Clara cell 16 KDa protein mitigates house dust mite-induced airway inflammation and damage via regulating airway epithelial cell apoptosis in a manner dependent on HMGB1-mediated signaling inhibition

BACKGROUND: House dust mite (HDM) inhalation can cause airway epithelial damage which is implicated in the process of airway inflammation in asthma. High mobility group box 1 (HMGB1) is critically required for cellular damage and apoptosis as an important endogenous danger signal. Recently, Clara ce...

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Detalles Bibliográficos
Autores principales:	Liu, Meixuan, Lu, Jingjing, Zhang, Qian, Zhang, Yunxuan, Guo, Zhongliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863538/ https://www.ncbi.nlm.nih.gov/pubmed/33541260 http://dx.doi.org/10.1186/s10020-021-00277-4

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