Cargando…

Evaluation of the relation between cardiac biomarkers and thorax computerized tomography findings in COVID-19 patients

Background: Troponin levels may be elevated in COVID-19 infection. The aim of this study was to the explore relation between troponin levels and COVID-19 severity. Materials & methods/Results: One hundred and forty consecutive patients with COVID-19 pneumonia were included. Diagnosis of COVID-19...

Descripción completa

Detalles Bibliográficos
Autores principales: Ileri, Cigdem, Dogan, Zekeriya, Ozben, Beste, Karaoglu, Cagla, Gunay, Nuran, Tigen, Kursat, Basat, Sema, Uyan, Cihangir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863677/
https://www.ncbi.nlm.nih.gov/pubmed/33501850
http://dx.doi.org/10.2217/bmm-2020-0388
_version_ 1783647527004798976
author Ileri, Cigdem
Dogan, Zekeriya
Ozben, Beste
Karaoglu, Cagla
Gunay, Nuran
Tigen, Kursat
Basat, Sema
Uyan, Cihangir
author_facet Ileri, Cigdem
Dogan, Zekeriya
Ozben, Beste
Karaoglu, Cagla
Gunay, Nuran
Tigen, Kursat
Basat, Sema
Uyan, Cihangir
author_sort Ileri, Cigdem
collection PubMed
description Background: Troponin levels may be elevated in COVID-19 infection. The aim of this study was to the explore relation between troponin levels and COVID-19 severity. Materials & methods/Results: One hundred and forty consecutive patients with COVID-19 pneumonia were included. Diagnosis of COVID-19 pneumonia was based on positive chest computed tomography (CT) findings. Quantitative PCR test was performed in all patients. Only 74 patients were quantitative PCR-positive. Twenty four patients had severe CT findings and 27 patients had progressive disease. These patients had significantly lower albumin and higher ferritin, D-dimer, lactate dehydrogenase, C-reactive protein, and high-sensitivity cardiac troponin I (hs-cTnI). Conclusion: COVID-19 patients with severe CT findings and progressive disease had higher hs-cTnI levels suggesting the use of hs-cTnI in risk stratification.
format Online
Article
Text
id pubmed-7863677
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Future Medicine Ltd
record_format MEDLINE/PubMed
spelling pubmed-78636772021-02-05 Evaluation of the relation between cardiac biomarkers and thorax computerized tomography findings in COVID-19 patients Ileri, Cigdem Dogan, Zekeriya Ozben, Beste Karaoglu, Cagla Gunay, Nuran Tigen, Kursat Basat, Sema Uyan, Cihangir Biomark Med Research Article Background: Troponin levels may be elevated in COVID-19 infection. The aim of this study was to the explore relation between troponin levels and COVID-19 severity. Materials & methods/Results: One hundred and forty consecutive patients with COVID-19 pneumonia were included. Diagnosis of COVID-19 pneumonia was based on positive chest computed tomography (CT) findings. Quantitative PCR test was performed in all patients. Only 74 patients were quantitative PCR-positive. Twenty four patients had severe CT findings and 27 patients had progressive disease. These patients had significantly lower albumin and higher ferritin, D-dimer, lactate dehydrogenase, C-reactive protein, and high-sensitivity cardiac troponin I (hs-cTnI). Conclusion: COVID-19 patients with severe CT findings and progressive disease had higher hs-cTnI levels suggesting the use of hs-cTnI in risk stratification. Future Medicine Ltd 2021-01-27 2021-01 /pmc/articles/PMC7863677/ /pubmed/33501850 http://dx.doi.org/10.2217/bmm-2020-0388 Text en © 2021 Future Medicine Ltd This work is licensed under the Creative Commons Attribution 4.0 License (http://creativecommons.org/licenses/by/4.0/)
spellingShingle Research Article
Ileri, Cigdem
Dogan, Zekeriya
Ozben, Beste
Karaoglu, Cagla
Gunay, Nuran
Tigen, Kursat
Basat, Sema
Uyan, Cihangir
Evaluation of the relation between cardiac biomarkers and thorax computerized tomography findings in COVID-19 patients
title Evaluation of the relation between cardiac biomarkers and thorax computerized tomography findings in COVID-19 patients
title_full Evaluation of the relation between cardiac biomarkers and thorax computerized tomography findings in COVID-19 patients
title_fullStr Evaluation of the relation between cardiac biomarkers and thorax computerized tomography findings in COVID-19 patients
title_full_unstemmed Evaluation of the relation between cardiac biomarkers and thorax computerized tomography findings in COVID-19 patients
title_short Evaluation of the relation between cardiac biomarkers and thorax computerized tomography findings in COVID-19 patients
title_sort evaluation of the relation between cardiac biomarkers and thorax computerized tomography findings in covid-19 patients
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863677/
https://www.ncbi.nlm.nih.gov/pubmed/33501850
http://dx.doi.org/10.2217/bmm-2020-0388
work_keys_str_mv AT ilericigdem evaluationoftherelationbetweencardiacbiomarkersandthoraxcomputerizedtomographyfindingsincovid19patients
AT doganzekeriya evaluationoftherelationbetweencardiacbiomarkersandthoraxcomputerizedtomographyfindingsincovid19patients
AT ozbenbeste evaluationoftherelationbetweencardiacbiomarkersandthoraxcomputerizedtomographyfindingsincovid19patients
AT karaoglucagla evaluationoftherelationbetweencardiacbiomarkersandthoraxcomputerizedtomographyfindingsincovid19patients
AT gunaynuran evaluationoftherelationbetweencardiacbiomarkersandthoraxcomputerizedtomographyfindingsincovid19patients
AT tigenkursat evaluationoftherelationbetweencardiacbiomarkersandthoraxcomputerizedtomographyfindingsincovid19patients
AT basatsema evaluationoftherelationbetweencardiacbiomarkersandthoraxcomputerizedtomographyfindingsincovid19patients
AT uyancihangir evaluationoftherelationbetweencardiacbiomarkersandthoraxcomputerizedtomographyfindingsincovid19patients