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Evaluation of the relation between cardiac biomarkers and thorax computerized tomography findings in COVID-19 patients
Background: Troponin levels may be elevated in COVID-19 infection. The aim of this study was to the explore relation between troponin levels and COVID-19 severity. Materials & methods/Results: One hundred and forty consecutive patients with COVID-19 pneumonia were included. Diagnosis of COVID-19...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Future Medicine Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863677/ https://www.ncbi.nlm.nih.gov/pubmed/33501850 http://dx.doi.org/10.2217/bmm-2020-0388 |
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author | Ileri, Cigdem Dogan, Zekeriya Ozben, Beste Karaoglu, Cagla Gunay, Nuran Tigen, Kursat Basat, Sema Uyan, Cihangir |
author_facet | Ileri, Cigdem Dogan, Zekeriya Ozben, Beste Karaoglu, Cagla Gunay, Nuran Tigen, Kursat Basat, Sema Uyan, Cihangir |
author_sort | Ileri, Cigdem |
collection | PubMed |
description | Background: Troponin levels may be elevated in COVID-19 infection. The aim of this study was to the explore relation between troponin levels and COVID-19 severity. Materials & methods/Results: One hundred and forty consecutive patients with COVID-19 pneumonia were included. Diagnosis of COVID-19 pneumonia was based on positive chest computed tomography (CT) findings. Quantitative PCR test was performed in all patients. Only 74 patients were quantitative PCR-positive. Twenty four patients had severe CT findings and 27 patients had progressive disease. These patients had significantly lower albumin and higher ferritin, D-dimer, lactate dehydrogenase, C-reactive protein, and high-sensitivity cardiac troponin I (hs-cTnI). Conclusion: COVID-19 patients with severe CT findings and progressive disease had higher hs-cTnI levels suggesting the use of hs-cTnI in risk stratification. |
format | Online Article Text |
id | pubmed-7863677 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Future Medicine Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-78636772021-02-05 Evaluation of the relation between cardiac biomarkers and thorax computerized tomography findings in COVID-19 patients Ileri, Cigdem Dogan, Zekeriya Ozben, Beste Karaoglu, Cagla Gunay, Nuran Tigen, Kursat Basat, Sema Uyan, Cihangir Biomark Med Research Article Background: Troponin levels may be elevated in COVID-19 infection. The aim of this study was to the explore relation between troponin levels and COVID-19 severity. Materials & methods/Results: One hundred and forty consecutive patients with COVID-19 pneumonia were included. Diagnosis of COVID-19 pneumonia was based on positive chest computed tomography (CT) findings. Quantitative PCR test was performed in all patients. Only 74 patients were quantitative PCR-positive. Twenty four patients had severe CT findings and 27 patients had progressive disease. These patients had significantly lower albumin and higher ferritin, D-dimer, lactate dehydrogenase, C-reactive protein, and high-sensitivity cardiac troponin I (hs-cTnI). Conclusion: COVID-19 patients with severe CT findings and progressive disease had higher hs-cTnI levels suggesting the use of hs-cTnI in risk stratification. Future Medicine Ltd 2021-01-27 2021-01 /pmc/articles/PMC7863677/ /pubmed/33501850 http://dx.doi.org/10.2217/bmm-2020-0388 Text en © 2021 Future Medicine Ltd This work is licensed under the Creative Commons Attribution 4.0 License (http://creativecommons.org/licenses/by/4.0/) |
spellingShingle | Research Article Ileri, Cigdem Dogan, Zekeriya Ozben, Beste Karaoglu, Cagla Gunay, Nuran Tigen, Kursat Basat, Sema Uyan, Cihangir Evaluation of the relation between cardiac biomarkers and thorax computerized tomography findings in COVID-19 patients |
title | Evaluation of the relation between cardiac biomarkers and thorax computerized tomography findings in COVID-19 patients |
title_full | Evaluation of the relation between cardiac biomarkers and thorax computerized tomography findings in COVID-19 patients |
title_fullStr | Evaluation of the relation between cardiac biomarkers and thorax computerized tomography findings in COVID-19 patients |
title_full_unstemmed | Evaluation of the relation between cardiac biomarkers and thorax computerized tomography findings in COVID-19 patients |
title_short | Evaluation of the relation between cardiac biomarkers and thorax computerized tomography findings in COVID-19 patients |
title_sort | evaluation of the relation between cardiac biomarkers and thorax computerized tomography findings in covid-19 patients |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863677/ https://www.ncbi.nlm.nih.gov/pubmed/33501850 http://dx.doi.org/10.2217/bmm-2020-0388 |
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