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Dendritic cell actin dynamics control contact duration and priming efficiency at the immunological synapse
Dendritic cells (DCs) are crucial for the priming of naive T cells and the initiation of adaptive immunity. Priming is initiated at a heterologous cell–cell contact, the immunological synapse (IS). While it is established that F-actin dynamics regulates signaling at the T cell side of the contact, l...
Autores principales: | Leithner, Alexander, Altenburger, Lukas M., Hauschild, Robert, Assen, Frank P., Rottner, Klemens, Stradal, Theresia E.B., Diz-Muñoz, Alba, Stein, Jens V., Sixt, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863705/ https://www.ncbi.nlm.nih.gov/pubmed/33533935 http://dx.doi.org/10.1083/jcb.202006081 |
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