Cargando…

Nebulin: Size matters for optimal muscle function

Gohlke et al. show the importance of nebulin size for optimal skeletal muscle function in animals of different body size.

Detalles Bibliográficos
Autor principal:	Pelin, Katarina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2021
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863720/ https://www.ncbi.nlm.nih.gov/pubmed/33533889 http://dx.doi.org/10.1085/jgp.202012848

Ejemplares similares

Expressing a Z-disk nebulin fragment in nebulin-deficient mouse muscle: effects on muscle structure and function
por: Li, Frank, et al.
Publicado: (2020)

Nebulin as a length regulator of thin filaments of vertebrate skeletal muscles: correlation of thin filament length, nebulin size, and epitope profile
Publicado: (1991)

Nebulin interactions with actin and tropomyosin are altered by disease-causing mutations
por: Marttila, Minttu, et al.
Publicado: (2014)

The Sarcomeric Protein Nebulin: Another Multifunctional Giant in Charge of Muscle Strength Optimization
por: Ottenheijm, Coen A. C., et al.
Publicado: (2012)

Nebulin no longer nebulous
por: Sedwick, Caitlin
Publicado: (2018)

New Insights into the Structural Roles of Nebulin in Skeletal Muscle
por: Ottenheijm, Coen A. C., et al.
Publicado: (2010)

Novel mutations in NEB cause abnormal nebulin expression and markedly impaired muscle force generation in severe nemaline myopathy
por: Lawlor, Michael W, et al.
Publicado: (2011)

A custom ddPCR method for the detection of copy number variations in the nebulin triplicate region
por: Sagath, Lydia, et al.
Publicado: (2022)

Muscle histopathology in nebulin-related nemaline myopathy: ultrastrastructural findings correlated to disease severity and genotype
por: Malfatti, Edoardo, et al.
Publicado: (2014)

Nebulin regulates the assembly and lengths of the thin filaments in striated muscle
por: McElhinny, Abigail S., et al.
Publicado: (2005)

Nebulin doesn't measure up
por: Short, Ben
Publicado: (2010)

Isolation of Nebulin from Rabbit Skeletal Muscle and Its Interaction with Actin
por: Chitose, Ryo, et al.
Publicado: (2010)

Two alternatively-spliced human nebulin isoforms with either exon 143 or exon 144 and their developmental regulation
por: Lam, Le Thanh, et al.
Publicado: (2018)

Nebulin: big protein with big responsibilities
por: Yuen, Michaela, et al.
Publicado: (2020)

Troponin activator augments muscle force in nemaline myopathy patients with nebulin mutations
por: de Winter, Josine Marieke, et al.
Publicado: (2013)

Nebulin stiffens the thin filament and augments cross-bridge interaction in skeletal muscle
por: Kiss, Balázs, et al.
Publicado: (2018)

Nebulin and Lmod2 are critical for specifying thin-filament length in skeletal muscle
por: Kiss, Balázs, et al.
Publicado: (2020)

Nebulin-deficient mice exhibit shorter thin filament lengths and reduced contractile function in skeletal muscle
por: Bang, Marie-Louise, et al.
Publicado: (2006)

Correction to: Expressing a Z-disk nebulin fragment innebulin-deficient mouse muscle: effects on muscle structure and function
por: Li, Frank, et al.
Publicado: (2020)

Clinical Manifestation of Nebulin-Associated Nemaline Myopathy
por: Moreno, Cristiane Araujo Martins, et al.
Publicado: (2023)

Nebulin binding impedes mutant desmin filament assembly
por: Baker, Laura K., et al.
Publicado: (2013)

The number of Z-repeats and super-repeats in nebulin greatly varies across vertebrates and scales with animal size
por: Gohlke, Jochen, et al.
Publicado: (2020)

Effect of levosimendan on the contractility of muscle fibers from nemaline myopathy patients with mutations in the nebulin gene
por: de Winter, Josine M, et al.
Publicado: (2015)

Nebulin regulates actin filament lengths by a stabilization mechanism
por: Pappas, Christopher T., et al.
Publicado: (2010)

Fast Skeletal Muscle Troponin Activation Increases Force of Mouse Fast Skeletal Muscle and Ameliorates Weakness Due to Nebulin-Deficiency
por: Lee, Eun-Jeong, et al.
Publicado: (2013)

Nebulin increases thin filament stiffness and force per cross-bridge in slow-twitch soleus muscle fibers
por: Kawai, Masataka, et al.
Publicado: (2018)

neb: a zebrafish model of nemaline myopathy due to nebulin mutation
por: Telfer, William R., et al.
Publicado: (2012)

Functional Characterization of the Intact Diaphragm in a Nebulin-Based Nemaline Myopathy (NM) Model-Effects of the Fast Skeletal Muscle Troponin Activator tirasemtiv
por: Lee, Eun-Jeong, et al.
Publicado: (2019)

Nebulin nemaline myopathy recapitulated in a compound heterozygous mouse model with both a missense and a nonsense mutation in Neb
por: Laitila, Jenni M., et al.
Publicado: (2020)

Distinct Families of Z-Line Targeting Modules in the Cooh-Terminal Region of Nebulin
por: Ojima, K., et al.
Publicado: (2000)

Nebulin and titin modulate cross-bridge cycling and length-dependent calcium sensitivity
por: Mijailovich, Srboljub M., et al.
Publicado: (2019)

It's not just size that matters: Challenges in studying obesity and female-specific cancers
por: Clarke, Megan A.
Publicado: (2021)

Size does matter: overcoming the adeno-associated virus packaging limit
por: Flotte, Terence R
Publicado: (2000)

The nebulin repeat protein Lasp regulates I-band architecture and filament spacing in myofibrils
por: Fernandes, Isabelle, et al.
Publicado: (2014)

Does Nebulin Make Tropomyosin Less Dynamic in Mature Myofibrils in Cross-Striated Myocytes?
por: Dube, DK, et al.
Publicado: (2014)

Contribution of the LIM Domain and Nebulin-Repeats to the Interaction of Lasp-2 with Actin Filaments and Focal Adhesions
por: Nakagawa, Hiroyuki, et al.
Publicado: (2009)

Variants in Nebulin (NEB) Are Linked to the Development of Familial Primary Angle Closure Glaucoma in Basset Hounds
por: Ahram, Dina F., et al.
Publicado: (2015)

Testing of therapies in a novel nebulin nemaline myopathy model demonstrate a lack of efficacy
por: Sztal, Tamar E., et al.
Publicado: (2018)

Omecamtiv mecarbil lowers the contractile deficit in a mouse model of nebulin-based nemaline myopathy
por: Lindqvist, Johan, et al.
Publicado: (2019)

Failure to identify modifiers of NEBULIN-related nemaline myopathy in two pre-clinical models of the disease
por: Qiu, Boyang, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_jnbiuna3m083dhebeg3264pvjn