Stop codon read-through of mammalian MTCH2 leading to an unstable isoform regulates mitochondrial membrane potential

Stop codon read-through (SCR) is a process of continuation of translation beyond a stop codon. This phenomenon, which occurs only in certain mRNAs under specific conditions, leads to a longer isoform with properties different from that of the canonical isoform. MTCH2, which encodes a mitochondrial p...

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Detalles Bibliográficos
Autores principales: Manjunath, Lekha E., Singh, Anumeha, Sahoo, Sarthak, Mishra, Ashutosh, Padmarajan, Jinsha, Basavaraju, Chaithanya G., Eswarappa, Sandeep M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Protein Synthesis and Degradation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863902/
https://www.ncbi.nlm.nih.gov/pubmed/33028634
http://dx.doi.org/10.1074/jbc.RA120.014253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863902/
https://www.ncbi.nlm.nih.gov/pubmed/33028634
http://dx.doi.org/10.1074/jbc.RA120.014253

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