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Inclusion Compound of Efavirenz and γ-Cyclodextrin: Solid State Studies and Effect on Solubility

Efavirenz is an antiretroviral drug of widespread use in the management of infections with human immunodeficiency virus type 1 (HIV-1). Efavirenz is also used in paediatrics, but due to its very poor aqueous solubility the liquid formulations available resort to oil-based excipients. In this report...

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Detalles Bibliográficos
Autores principales: Braga, Susana Santos, El-Saleh, Firas, Lysenko, Karyna, Paz, Filipe A. Almeida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863942/
https://www.ncbi.nlm.nih.gov/pubmed/33498239
http://dx.doi.org/10.3390/molecules26030519