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Early Stages of Alzheimer's Disease: Evolving the Care Team for Optimal Patient Management

Alzheimer's disease (AD) is a progressive, neurodegenerative disease that creates complex challenges and a significant burden for patients and caregivers. Although underlying pathological changes due to AD may be detected in research studies decades prior to symptom onset, many patients in the...

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Autores principales: Galvin, James E., Aisen, Paul, Langbaum, Jessica B., Rodriguez, Eric, Sabbagh, Marwan, Stefanacci, Richard, Stern, Robert A., Vassey, Elizabeth A., de Wilde, Arno, West, Neva, Rubino, Ivana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863984/
https://www.ncbi.nlm.nih.gov/pubmed/33551954
http://dx.doi.org/10.3389/fneur.2020.592302
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author Galvin, James E.
Aisen, Paul
Langbaum, Jessica B.
Rodriguez, Eric
Sabbagh, Marwan
Stefanacci, Richard
Stern, Robert A.
Vassey, Elizabeth A.
de Wilde, Arno
West, Neva
Rubino, Ivana
author_facet Galvin, James E.
Aisen, Paul
Langbaum, Jessica B.
Rodriguez, Eric
Sabbagh, Marwan
Stefanacci, Richard
Stern, Robert A.
Vassey, Elizabeth A.
de Wilde, Arno
West, Neva
Rubino, Ivana
author_sort Galvin, James E.
collection PubMed
description Alzheimer's disease (AD) is a progressive, neurodegenerative disease that creates complex challenges and a significant burden for patients and caregivers. Although underlying pathological changes due to AD may be detected in research studies decades prior to symptom onset, many patients in the early stages of AD remain undiagnosed in clinical practice. Increasing evidence points to the importance of an early and accurate AD diagnosis to optimize outcomes for patients and their families, yet many barriers remain along the diagnostic journey. Through a series of international working group meetings, a diverse group of experts contributed their perspectives to create a blueprint for a patient-centered diagnostic journey for individuals in the early stages of AD and an evolving, transdisciplinary care team. Here, we discuss key learnings, implications, and recommendations.
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spelling pubmed-78639842021-02-06 Early Stages of Alzheimer's Disease: Evolving the Care Team for Optimal Patient Management Galvin, James E. Aisen, Paul Langbaum, Jessica B. Rodriguez, Eric Sabbagh, Marwan Stefanacci, Richard Stern, Robert A. Vassey, Elizabeth A. de Wilde, Arno West, Neva Rubino, Ivana Front Neurol Neurology Alzheimer's disease (AD) is a progressive, neurodegenerative disease that creates complex challenges and a significant burden for patients and caregivers. Although underlying pathological changes due to AD may be detected in research studies decades prior to symptom onset, many patients in the early stages of AD remain undiagnosed in clinical practice. Increasing evidence points to the importance of an early and accurate AD diagnosis to optimize outcomes for patients and their families, yet many barriers remain along the diagnostic journey. Through a series of international working group meetings, a diverse group of experts contributed their perspectives to create a blueprint for a patient-centered diagnostic journey for individuals in the early stages of AD and an evolving, transdisciplinary care team. Here, we discuss key learnings, implications, and recommendations. Frontiers Media S.A. 2021-01-22 /pmc/articles/PMC7863984/ /pubmed/33551954 http://dx.doi.org/10.3389/fneur.2020.592302 Text en Copyright © 2021 Galvin, Aisen, Langbaum, Rodriguez, Sabbagh, Stefanacci, Stern, Vassey, de Wilde, West and Rubino. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Galvin, James E.
Aisen, Paul
Langbaum, Jessica B.
Rodriguez, Eric
Sabbagh, Marwan
Stefanacci, Richard
Stern, Robert A.
Vassey, Elizabeth A.
de Wilde, Arno
West, Neva
Rubino, Ivana
Early Stages of Alzheimer's Disease: Evolving the Care Team for Optimal Patient Management
title Early Stages of Alzheimer's Disease: Evolving the Care Team for Optimal Patient Management
title_full Early Stages of Alzheimer's Disease: Evolving the Care Team for Optimal Patient Management
title_fullStr Early Stages of Alzheimer's Disease: Evolving the Care Team for Optimal Patient Management
title_full_unstemmed Early Stages of Alzheimer's Disease: Evolving the Care Team for Optimal Patient Management
title_short Early Stages of Alzheimer's Disease: Evolving the Care Team for Optimal Patient Management
title_sort early stages of alzheimer's disease: evolving the care team for optimal patient management
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863984/
https://www.ncbi.nlm.nih.gov/pubmed/33551954
http://dx.doi.org/10.3389/fneur.2020.592302
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