The Antidepressant-Like Effects of a Clinically Relevant Dose of Ketamine Are Accompanied by Biphasic Alterations in Working Memory in the Wistar Kyoto Rat Model of Depression

Major depressive disorder (MDD) is the leading cause of disability worldwide. The majority of antidepressant drugs require several weeks or months of treatment to demonstrate efficacy and a subset of patients are resistant to such interventions. Ketamine demonstrates rapid and long-lasting antidepre...

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Detalles Bibliográficos
Autores principales: McDonnell, Conor W., Dunphy-Doherty, Fionn, Rouine, Jennifer, Bianchi, Massimiliano, Upton, Neil, Sokolowska, Ewa, Prenderville, Jack A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863985/
https://www.ncbi.nlm.nih.gov/pubmed/33551869
http://dx.doi.org/10.3389/fpsyt.2020.599588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863985/
https://www.ncbi.nlm.nih.gov/pubmed/33551869
http://dx.doi.org/10.3389/fpsyt.2020.599588

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