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Peptidoglycan analysis reveals that synergistic deacetylase activity in vegetative Clostridium difficile impacts the host response
Clostridium difficile is an anaerobic and spore-forming bacterium responsible for 15–25% of postantibiotic diarrhea and 95% of pseudomembranous colitis. Peptidoglycan is a crucial element of the bacterial cell wall that is exposed to the host, making it an important target for the innate immune syst...
Autores principales: | Coullon, Héloise, Rifflet, Aline, Wheeler, Richard, Janoir, Claire, Boneca, Ivo G., Candela, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864072/ https://www.ncbi.nlm.nih.gov/pubmed/32978253 http://dx.doi.org/10.1074/jbc.RA119.012442 |
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