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VBP1 modulates Wnt/β-catenin signaling by mediating the stability of the transcription factors TCF/LEFs
The Wnt/β-catenin pathway is one of the major pathways that regulates embryonic development, adult homeostasis, and stem cell self-renewal. In this pathway, transcription factors T-cell factor and lymphoid enhancer factor (TCF/LEF) serve as a key switch to repress or activate Wnt target gene transcr...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864075/ https://www.ncbi.nlm.nih.gov/pubmed/32989053 http://dx.doi.org/10.1074/jbc.RA120.015282 |