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Calpain activation mediates microgravity-induced myocardial abnormalities in mice via p38 and ERK1/2 MAPK pathways

The human cardiovascular system has adapted to function optimally in Earth's 1G gravity, and microgravity conditions cause myocardial abnormalities, including atrophy and dysfunction. However, the underlying mechanisms linking microgravity and cardiac anomalies are incompletely understood. In t...

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Detalles Bibliográficos
Autores principales:	Liang, Liwen, Li, Huili, Cao, Ting, Qu, Lina, Zhang, Lulu, Fan, Guo-Chang, Greer, Peter A., Li, Jianmin, Jones, Douglas L., Peng, Tianqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Molecular Bases of Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864076/ https://www.ncbi.nlm.nih.gov/pubmed/32989050 http://dx.doi.org/10.1074/jbc.RA119.011890

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