Secretory galectin-3 induced by glucocorticoid stress triggers stemness exhaustion of hepatic progenitor cells

Adult progenitor cell populations typically exist in a quiescent state within a controlled niche environment. However, various stresses or forms of damage can disrupt this state, which often leads to dysfunction and aging. We built a glucocorticoid (GC)-induced liver damage model of mice, found that...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Fan, Zhang, Fan, Ji, Xueying, Jiang, Xin, Xue, Mengjuan, Yu, Huiyuan, Hu, Xiaona, Bao, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864077/
https://www.ncbi.nlm.nih.gov/pubmed/32989051
http://dx.doi.org/10.1074/jbc.RA120.012974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864077/
https://www.ncbi.nlm.nih.gov/pubmed/32989051
http://dx.doi.org/10.1074/jbc.RA120.012974

Ejemplares similares