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Secretory galectin-3 induced by glucocorticoid stress triggers stemness exhaustion of hepatic progenitor cells
Adult progenitor cell populations typically exist in a quiescent state within a controlled niche environment. However, various stresses or forms of damage can disrupt this state, which often leads to dysfunction and aging. We built a glucocorticoid (GC)-induced liver damage model of mice, found that...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864077/ https://www.ncbi.nlm.nih.gov/pubmed/32989051 http://dx.doi.org/10.1074/jbc.RA120.012974 |