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Pluripotency of embryonic stem cells lacking clathrin-mediated endocytosis cannot be rescued by restoring cellular stiffness

Mouse embryonic stem cells (mESCs) display unique mechanical properties, including low cellular stiffness in contrast to differentiated cells, which are stiffer. We have previously shown that mESCs lacking the clathrin heavy chain (Cltc), an essential component for clathrin-mediated endocytosis (CME...

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Detalles Bibliográficos
Autores principales: Mote, Ridim D., Yadav, Jyoti, Singh, Surya Bansi, Tiwari, Mahak, V, Shinde Laxmikant, Patil, Shivprasad, Subramanyam, Deepa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864080/
https://www.ncbi.nlm.nih.gov/pubmed/33087446
http://dx.doi.org/10.1074/jbc.AC120.014343