Cargando…
Inhibition of the invasion and metastasis of mammary carcinoma cells by NBD peptide targeting S100A4 via the suppression of the Sp1/MMP-14 axis
A synthetic peptide that blocks the interaction between the metastasis-enhancing calcium-binding protein, S100A4, and its effector protein, methionine aminopeptidase 2 (MetAP2) (the NBD peptide), was previously demonstrated to inhibit the angiogenesis of endothelial cells, leading to the regression...
Autores principales: | Takenaga, Keizo, Ochiya, Takahiro, Endo, Hideya |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864152/ https://www.ncbi.nlm.nih.gov/pubmed/33650647 http://dx.doi.org/10.3892/ijo.2021.5173 |
Ejemplares similares
-
Silencing of S100A4, a metastasis-associated protein, in endothelial cells inhibits tumor angiogenesis and growth
por: Ochiya, Takahiro, et al.
Publicado: (2013) -
Efficient inhibition of tumor angiogenesis and growth by a synthetic peptide blocking S100A4-methionine aminopeptidase 2 interaction
por: Ochiya, Takahiro, et al.
Publicado: (2015) -
The NBD-NBD interface is not the sole determinant for transport in ABC transporters
por: Dönmez, Yaprak, et al.
Publicado: (2012) -
Involvement of Sl00–related Calcium–binding Protein pEL98 (or mts1) in Cell Motility and Tumor Cell Invasion
por: Takenaga, Keizo, et al.
Publicado: (1994) -
Activation of MMP‐9 by membrane type‐1 MMP/MMP‐2 axis stimulates tumor metastasis
por: Li, Zichen, et al.
Publicado: (2017)