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In Vitro Systematic Drug Testing Reveals Carboplatin, Paclitaxel, and Alpelisib as a Potential Novel Combination Treatment for Adult Granulosa Cell Tumors

SIMPLE SUMMARY: Granulosa cell tumor treatment is challenging as there are few effective options besides surgery. In this study, we obtained tumor tissue from patients at surgery and cultured tumor cells in the laboratory. After sufficient expansion, we tested the effects of current treatments, such...

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Detalles Bibliográficos
Autores principales: Roze, Joline, Sendino Garví, Elena, Stelloo, Ellen, Stangl, Christina, Sereno, Ferdinando, Duran, Karen, Groeneweg, Jolijn, Paijens, Sterre, Nijman, Hans, van Meurs, Hannah, van Lonkhuijzen, Luc, Piek, Jurgen, Lok, Christianne, Jonges, Geertruida, Witteveen, Petronella, Verheijen, René, van Haaften, Gijs, Zweemer, Ronald, Monroe, Glen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864192/
https://www.ncbi.nlm.nih.gov/pubmed/33498451
http://dx.doi.org/10.3390/cancers13030368