Nicolau syndrome following intramuscular benzathine penicillin injection: a case report

Nicolau syndrome (NS) is a rare injection site reaction, following intramuscular injection of drugs characterized by severe pain, skin discoloration and varying level of tissue necrosis. The case outcomes vary from severe pain, atrophic ulcers to sepsis and limb amputation. We describe a case of the...

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Autores principales: Phiri, Walaza, Musonda, Maen Shulammite, Kyakilika, Kebby, Miyoba, Michelo Haluuma, Malumani, Malan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864265/
https://www.ncbi.nlm.nih.gov/pubmed/33598090
http://dx.doi.org/10.11604/pamj.2020.37.276.21850
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author Phiri, Walaza
Musonda, Maen Shulammite
Kyakilika, Kebby
Miyoba, Michelo Haluuma
Malumani, Malan
author_facet Phiri, Walaza
Musonda, Maen Shulammite
Kyakilika, Kebby
Miyoba, Michelo Haluuma
Malumani, Malan
author_sort Phiri, Walaza
collection PubMed
description Nicolau syndrome (NS) is a rare injection site reaction, following intramuscular injection of drugs characterized by severe pain, skin discoloration and varying level of tissue necrosis. The case outcomes vary from severe pain, atrophic ulcers to sepsis and limb amputation. We describe a case of the five-year-old girl with diagnosis of NS after intramuscular benzathine penicillin injection. The case was complicated with above the knee amputation of lower limb. This case report intends to remind clinicians that such rare cases should always be thought of in all patients receiving whatsoever drug via intramuscular injections.
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spelling pubmed-78642652021-02-16 Nicolau syndrome following intramuscular benzathine penicillin injection: a case report Phiri, Walaza Musonda, Maen Shulammite Kyakilika, Kebby Miyoba, Michelo Haluuma Malumani, Malan Pan Afr Med J Case Report Nicolau syndrome (NS) is a rare injection site reaction, following intramuscular injection of drugs characterized by severe pain, skin discoloration and varying level of tissue necrosis. The case outcomes vary from severe pain, atrophic ulcers to sepsis and limb amputation. We describe a case of the five-year-old girl with diagnosis of NS after intramuscular benzathine penicillin injection. The case was complicated with above the knee amputation of lower limb. This case report intends to remind clinicians that such rare cases should always be thought of in all patients receiving whatsoever drug via intramuscular injections. The African Field Epidemiology Network 2020-11-26 /pmc/articles/PMC7864265/ /pubmed/33598090 http://dx.doi.org/10.11604/pamj.2020.37.276.21850 Text en Copyright: Walaza Phiri et al. https://creativecommons.org/licenses/by/4.0 The Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Phiri, Walaza
Musonda, Maen Shulammite
Kyakilika, Kebby
Miyoba, Michelo Haluuma
Malumani, Malan
Nicolau syndrome following intramuscular benzathine penicillin injection: a case report
title Nicolau syndrome following intramuscular benzathine penicillin injection: a case report
title_full Nicolau syndrome following intramuscular benzathine penicillin injection: a case report
title_fullStr Nicolau syndrome following intramuscular benzathine penicillin injection: a case report
title_full_unstemmed Nicolau syndrome following intramuscular benzathine penicillin injection: a case report
title_short Nicolau syndrome following intramuscular benzathine penicillin injection: a case report
title_sort nicolau syndrome following intramuscular benzathine penicillin injection: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864265/
https://www.ncbi.nlm.nih.gov/pubmed/33598090
http://dx.doi.org/10.11604/pamj.2020.37.276.21850
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