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Impact of gestational low-protein intake on embryonic kidney microRNA expression and in nephron progenitor cells of the male fetus

BACKGROUND: Here, we have demonstrated that gestational low-protein (LP) intake offspring present lower birth weight, reduced nephron numbers, renal salt excretion, arterial hypertension, and renal failure development compared to regular protein (NP) intake rats in adulthood. We evaluated the expres...

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Detalles Bibliográficos
Autores principales: Sene, Letícia de Barros, Scarano, Wellerson Rodrigo, Zapparoli, Adriana, Gontijo, José Antônio Rocha, Boer, Patrícia Aline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864410/
https://www.ncbi.nlm.nih.gov/pubmed/33544723
http://dx.doi.org/10.1371/journal.pone.0246289