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Impact of gestational low-protein intake on embryonic kidney microRNA expression and in nephron progenitor cells of the male fetus
BACKGROUND: Here, we have demonstrated that gestational low-protein (LP) intake offspring present lower birth weight, reduced nephron numbers, renal salt excretion, arterial hypertension, and renal failure development compared to regular protein (NP) intake rats in adulthood. We evaluated the expres...
Autores principales: | Sene, Letícia de Barros, Scarano, Wellerson Rodrigo, Zapparoli, Adriana, Gontijo, José Antônio Rocha, Boer, Patrícia Aline |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864410/ https://www.ncbi.nlm.nih.gov/pubmed/33544723 http://dx.doi.org/10.1371/journal.pone.0246289 |
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