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Decreased content of ascorbic acid (vitamin C) in the brain of knockout mouse models of Na(+),K(+)-ATPase-related neurologic disorders

Na(+),K(+)-ATPase is a crucial protein responsible for maintaining the electrochemical gradients across the cell membrane. The Na(+),K(+)-ATPase is comprised of catalytic α, β, and γ subunits. In adult brains, the α3 subunit, encoded by ATP1A3, is predominantly expressed in neurons, whereas the α2 s...

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Detalles Bibliográficos
Autores principales:	Ikeda, Keiko, Tienda, Adriana A., Harrison, Fiona E., Kawakami, Kiyoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864419/ https://www.ncbi.nlm.nih.gov/pubmed/33544780 http://dx.doi.org/10.1371/journal.pone.0246678

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