Genetic and Environmental Factors Influence the Pleomorphy of LRRK2 Parkinsonism

Missense mutations in the LRRK2 gene were first identified as a pathogenic cause of Parkinson’s disease (PD) in 2004. Soon thereafter, a founder mutation in LRRK2, p.G2019S (rs34637584), was described, and it is now estimated that there are approximately 100,000 people worldwide carrying this risk v...

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Detalles Bibliográficos
Autores principales: Chittoor-Vinod, Vinita G., Nichols, R. Jeremy, Schüle, Birgitt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864502/
https://www.ncbi.nlm.nih.gov/pubmed/33494262
http://dx.doi.org/10.3390/ijms22031045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864502/
https://www.ncbi.nlm.nih.gov/pubmed/33494262
http://dx.doi.org/10.3390/ijms22031045

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