A combinational chemo-immune therapy using an enzyme-sensitive nanoplatform for dual-drug delivery to specific sites by cascade targeting

Nanoparticle-based drug delivery faces challenges from the imprecise targeted delivery and the low bioavailability of drugs due to complex biological barriers. Here, we designed cascade-targeting, dual drug–loaded, core-shell nanoparticles (DLTPT) consisting of CD44-targeting hyaluronic acid shells...

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Detalles Bibliográficos
Autores principales: He, Yanmei, Lei, Lei, Cao, Jun, Yang, Xiaotong, Cai, Shengsheng, Tong, Fan, Huang, Dennis, Mei, Heng, Luo, Kui, Gao, Huile, He, Bin, Peppas, Nicholas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864565/
https://www.ncbi.nlm.nih.gov/pubmed/33547067
http://dx.doi.org/10.1126/sciadv.aba0776

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