The fibrinolytic system enables the onset of Plasmodium infection in the mosquito vector and the mammalian host

Plasmodium parasites must migrate across proteinaceous matrices to infect the mosquito and vertebrate hosts. Plasmin, a mammalian serine protease, degrades extracellular matrix proteins allowing cell migration through tissues. We report that Plasmodium gametes recruit human plasminogen to their surf...

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Detalles Bibliográficos
Autores principales: Alves e Silva, Thiago Luiz, Radtke, Andrea, Balaban, Amanda, Pascini, Tales Vicari, Pala, Zarna Rajeshkumar, Roth, Alison, Alvarenga, Patricia H., Jeong, Yeong Je, Olivas, Janet, Ghosh, Anil K., Bui, Hanhvy, Pybus, Brandon S., Sinnis, Photini, Jacobs-Lorena, Marcelo, Vega-Rodríguez, Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864569/
https://www.ncbi.nlm.nih.gov/pubmed/33547079
http://dx.doi.org/10.1126/sciadv.abe3362

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