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Structural basis for transcription complex disruption by the Mfd translocase

Transcription-coupled repair (TCR) is a sub-pathway of nucleotide excision repair (NER) that preferentially removes lesions from the template-strand (t-strand) that stall RNA polymerase (RNAP) elongation complexes (ECs). Mfd mediates TCR in bacteria by removing the stalled RNAP concealing the lesion...

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Detalles Bibliográficos
Autores principales:	Kang, Jin Young, Llewellyn, Eliza, Chen, James, Olinares, Paul Dominic B, Brewer, Joshua, Chait, Brian T, Campbell, Elizabeth A, Darst, Seth A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Structural Biology and Molecular Biophysics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864632/ https://www.ncbi.nlm.nih.gov/pubmed/33480355 http://dx.doi.org/10.7554/eLife.62117

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