High-resolution mapping of the neutralizing and binding specificities of polyclonal sera post-HIV Env trimer vaccination

Mapping polyclonal serum responses is critical to rational vaccine design. However, most high-resolution mapping approaches involve isolating and characterizing individual antibodies, which incompletely defines the polyclonal response. Here we use two complementary approaches to directly map the spe...

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Detalles Bibliográficos
Autores principales: Dingens, Adam S, Pratap, Payal, Malone, Keara, Hilton, Sarah K, Ketas, Thomas, Cottrell, Christopher A, Overbaugh, Julie, Moore, John P, Klasse, PJ, Ward, Andrew B, Bloom, Jesse D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864656/
https://www.ncbi.nlm.nih.gov/pubmed/33438580
http://dx.doi.org/10.7554/eLife.64281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864656/
https://www.ncbi.nlm.nih.gov/pubmed/33438580
http://dx.doi.org/10.7554/eLife.64281

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