Cargando…
System Pharmacology-Based Strategy to Decode the Synergistic Mechanism of GanDouLing for Wilson's Disease
RESULTS: Firstly, 324 active compounds have been identified in the GDL formula. Meanwhile, we identified 1496 human genes which are related to WD or liver cirrhosis. Functional and pathway enrichment analysis indicated that NOD-like receptor signaling pathway, bile secretion, calcium signaling pathw...
Autores principales: | Zhang, Juan, Chen, Hong, Bao, Yuancheng, Xie, Daojun, Yang, Wenming, Jiang, Huaizhou, Dong, Ting, Han, Hui |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864764/ https://www.ncbi.nlm.nih.gov/pubmed/33564316 http://dx.doi.org/10.1155/2021/1248920 |
Ejemplares similares
-
GanDouLing promotes proliferation and differentiation of neural stem cells in the mouse model of Wilson’s disease
por: Dong, Ting, et al.
Publicado: (2021) -
GanDouLing combined with Penicillamine improves cerebrovascular injury via PERK/eIF2α/CHOP endoplasmic reticulum stress pathway in the mouse model of Wilson’s disease
por: Chen, Yonghua, et al.
Publicado: (2018) -
Integrated Metabolomics and Network Pharmacology to Reveal the Mechanisms of Gandouling Tablets Against Copper-Overload-Induced Neuronal Injury in Rats with Wilson’s Disease
por: Chen, Li, et al.
Publicado: (2023) -
Comprehensive RNA-Seq Analysis of Potential Therapeutic Targets of Gan–Dou–Fu–Mu Decoction for Treatment of Wilson Disease Using a Toxic Milk Mouse Model
por: Wei, Taohua, et al.
Publicado: (2021) -
Gandouling Mitigates CuSO(4)-Induced Heart Injury in Rats
por: Fang, Shuzhen, et al.
Publicado: (2022)