Sperm DNA methylation mediates the association of male age on reproductive outcomes among couples undergoing infertility treatment

Parental age at time of offspring conception is increasing in developed countries. Advanced male age is associated with decreased reproductive success and increased risk of adverse neurodevelopmental outcomes in offspring. Mechanisms for these male age effects remain unclear, but changes in sperm DN...

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Detalles Bibliográficos
Autores principales: Oluwayiose, Oladele A., Wu, Haotian, Saddiki, Hachem, Whitcomb, Brian W., Balzer, Laura B., Brandon, Nicole, Suvorov, Alexander, Tayyab, Rahil, Sites, Cynthia K., Hill, Lisa, Marcho, Chelsea, Pilsner, J. Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864951/
https://www.ncbi.nlm.nih.gov/pubmed/33547328
http://dx.doi.org/10.1038/s41598-020-80857-2

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