Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology

Serum liver enzyme concentrations are the most frequently-used laboratory markers of liver disease, a major cause of mortality. We conduct a meta-analysis of genome-wide association studies of liver enzymes from UK BioBank and BioBank Japan. We identified 160 previously-unreported independent alanin...

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Detalles Bibliográficos
Autores principales: Chen, Vincent L., Du, Xiaomeng, Chen, Yanhua, Kuppa, Annapurna, Handelman, Samuel K., Vohnoutka, Rishel B., Peyser, Patricia A., Palmer, Nicholette D., Bielak, Lawrence F., Halligan, Brian, Speliotes, Elizabeth K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865025/
https://www.ncbi.nlm.nih.gov/pubmed/33547301
http://dx.doi.org/10.1038/s41467-020-20870-1

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