Efficient detection and post-surgical monitoring of colon cancer with a multi-marker DNA methylation liquid biopsy

Multiplex assays, involving the simultaneous use of multiple circulating tumor DNA (ctDNA) markers, can improve the performance of liquid biopsies so that they are highly predictive of cancer recurrence. We have developed a single-tube methylation-specific quantitative PCR assay (mqMSP) that uses 10...

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Detalles Bibliográficos
Autores principales: Jin, Shengnan, Zhu, Dewen, Shao, Fanggui, Chen, Shiliang, Guo, Ying, Li, Kuan, Wang, Yourong, Ding, Rongxiu, Gao, Lingjia, Ma, Wen, Lu, Tong, Li, Dandan, Zhang, Zhengzheng, Cai, Suili, Liang, Xue, Song, Huayu, Ji, Ling, Li, Jinlei, Zheng, Zhihai, Jiang, Feizhao, Wu, Xiaoli, Luan, Ju, Zhang, Huxiang, Yang, Zhengquan, Cantor, Charles R., Xu, Chang, Ding, Chunming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865146/
https://www.ncbi.nlm.nih.gov/pubmed/33495330
http://dx.doi.org/10.1073/pnas.2017421118

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