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PROTACs and Building Blocks: The 2D Chemical Space in Very Early Drug Discovery
Targeted protein degradation by PROTACs has emerged as a new modality for the knockdown of a range of proteins, and, more recently, it has become increasingly clear that the PROTAC chemical space requires characterization through a pool of ad hoc physicochemical descriptors. In this study, a new dat...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865272/ https://www.ncbi.nlm.nih.gov/pubmed/33525371 http://dx.doi.org/10.3390/molecules26030672 |