Cargando…
PLEKHA7, an Apical Adherens Junction Protein, Suppresses Inflammatory Breast Cancer in the Context of High E-Cadherin and p120-Catenin Expression
Inflammatory breast cancer is a highly aggressive form of breast cancer that forms clusters of tumor emboli in dermal lymphatics and readily metastasizes. These cancers express high levels of E-cadherin, the major mediator of adherens junctions, which enhances formation of tumor emboli. Previous stu...
Autores principales: | Pence, Lindy J., Kourtidis, Antonis, Feathers, Ryan W., Haddad, Mary T., Sotiriou, Sotiris, Decker, Paul A., Nassar, Aziza, Ocal, Idris T., Shah, Sejal S., Anastasiadis, Panos Z. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865280/ https://www.ncbi.nlm.nih.gov/pubmed/33525380 http://dx.doi.org/10.3390/ijms22031275 |
Ejemplares similares
-
Origin and Evolution of the Multifaceted Adherens Junction Component Plekha7
por: Kourtidis, Antonis, et al.
Publicado: (2022) -
Simultaneous E-cadherin and PLEKHA7 expression negatively affects E-cadherin/EGFR mediated ovarian cancer cell growth
por: Rea, Katia, et al.
Publicado: (2018) -
Cadherin complexes recruit mRNAs and RISC to regulate epithelial cell signaling
por: Kourtidis, Antonis, et al.
Publicado: (2017) -
PLEKHA7 Is an Adherens Junction Protein with a Tissue Distribution and Subcellular Localization Distinct from ZO-1 and E-Cadherin
por: Pulimeno, Pamela, et al.
Publicado: (2010) -
Pro-Tumorigenic Phosphorylation of p120 Catenin in Renal and Breast Cancer
por: Kourtidis, Antonis, et al.
Publicado: (2015)