Natriuretic Peptide Expression and Function in GH3 Somatolactotropes and Feline Somatotrope Pituitary Tumours

Patients harbouring mutations in genes encoding C-type natriuretic peptide (CNP; NPPC) or its receptor guanylyl cyclase B (GC-B, NPR2) suffer from severe growth phenotypes; loss-of-function mutations cause achondroplasia, whereas gain-of-function mutations cause skeletal overgrowth. Although most of...

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Detalles Bibliográficos
Autores principales: Mirczuk, Samantha M., Scudder, Christopher J., Read, Jordan E., Crossley, Victoria J., Regan, Jacob T., Richardson, Karen M., Simbi, Bigboy, McArdle, Craig A., Church, David B., Fenn, Joseph, Kenny, Patrick J., Volk, Holger A., Wheeler-Jones, Caroline P., Korbonits, Márta, Niessen, Stijn J., McGonnell, Imelda M., Fowkes, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865297/
https://www.ncbi.nlm.nih.gov/pubmed/33499110
http://dx.doi.org/10.3390/ijms22031076

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