Identification of Novel Substrates for cGMP Dependent Protein Kinase (PKG) through Kinase Activity Profiling to Understand Its Putative Role in Inherited Retinal Degeneration

Inherited retinal degenerative diseases (IRDs), which ultimately lead to photoreceptor cell death, are characterized by high genetic heterogeneity. Many IRD-associated genetic defects affect 3′,5′-cyclic guanosine monophosphate (cGMP) levels. cGMP-dependent protein kinases (PKGI and PKGII) have emer...

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Detalles Bibliográficos
Autores principales: Roy, Akanksha, Groten, John, Marigo, Valeria, Tomar, Tushar, Hilhorst, Riet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865299/
https://www.ncbi.nlm.nih.gov/pubmed/33503999
http://dx.doi.org/10.3390/ijms22031180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865299/
https://www.ncbi.nlm.nih.gov/pubmed/33503999
http://dx.doi.org/10.3390/ijms22031180

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