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Phytochemicals in Gynecological Cancer Prevention

Gynecological cancer confers an enormous burden among women worldwide. Accumulating evidence points to the role of phytochemicals in preventing cervical, endometrial, and ovarian cancer. Experimental studies emphasize the chemopreventive and therapeutic potential of plant-derived substances by inhib...

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Detalles Bibliográficos
Autores principales: Woźniak, Marta, Krajewski, Rafał, Makuch, Sebastian, Agrawal, Siddarth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865323/
https://www.ncbi.nlm.nih.gov/pubmed/33530651
http://dx.doi.org/10.3390/ijms22031219
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author Woźniak, Marta
Krajewski, Rafał
Makuch, Sebastian
Agrawal, Siddarth
author_facet Woźniak, Marta
Krajewski, Rafał
Makuch, Sebastian
Agrawal, Siddarth
author_sort Woźniak, Marta
collection PubMed
description Gynecological cancer confers an enormous burden among women worldwide. Accumulating evidence points to the role of phytochemicals in preventing cervical, endometrial, and ovarian cancer. Experimental studies emphasize the chemopreventive and therapeutic potential of plant-derived substances by inhibiting the early stages of carcinogenesis or improving the efficacy of traditional chemotherapeutic agents. Moreover, a number of epidemiological studies have investigated associations between a plant-based diet and cancer risk. This literature review summarizes the current knowledge on the phytochemicals with proven antitumor activity, emphasizing their effectiveness and mechanism of action in gynecological cancer.
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spelling pubmed-78653232021-02-07 Phytochemicals in Gynecological Cancer Prevention Woźniak, Marta Krajewski, Rafał Makuch, Sebastian Agrawal, Siddarth Int J Mol Sci Review Gynecological cancer confers an enormous burden among women worldwide. Accumulating evidence points to the role of phytochemicals in preventing cervical, endometrial, and ovarian cancer. Experimental studies emphasize the chemopreventive and therapeutic potential of plant-derived substances by inhibiting the early stages of carcinogenesis or improving the efficacy of traditional chemotherapeutic agents. Moreover, a number of epidemiological studies have investigated associations between a plant-based diet and cancer risk. This literature review summarizes the current knowledge on the phytochemicals with proven antitumor activity, emphasizing their effectiveness and mechanism of action in gynecological cancer. MDPI 2021-01-26 /pmc/articles/PMC7865323/ /pubmed/33530651 http://dx.doi.org/10.3390/ijms22031219 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Woźniak, Marta
Krajewski, Rafał
Makuch, Sebastian
Agrawal, Siddarth
Phytochemicals in Gynecological Cancer Prevention
title Phytochemicals in Gynecological Cancer Prevention
title_full Phytochemicals in Gynecological Cancer Prevention
title_fullStr Phytochemicals in Gynecological Cancer Prevention
title_full_unstemmed Phytochemicals in Gynecological Cancer Prevention
title_short Phytochemicals in Gynecological Cancer Prevention
title_sort phytochemicals in gynecological cancer prevention
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865323/
https://www.ncbi.nlm.nih.gov/pubmed/33530651
http://dx.doi.org/10.3390/ijms22031219
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