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Phytochemicals in Gynecological Cancer Prevention
Gynecological cancer confers an enormous burden among women worldwide. Accumulating evidence points to the role of phytochemicals in preventing cervical, endometrial, and ovarian cancer. Experimental studies emphasize the chemopreventive and therapeutic potential of plant-derived substances by inhib...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865323/ https://www.ncbi.nlm.nih.gov/pubmed/33530651 http://dx.doi.org/10.3390/ijms22031219 |
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author | Woźniak, Marta Krajewski, Rafał Makuch, Sebastian Agrawal, Siddarth |
author_facet | Woźniak, Marta Krajewski, Rafał Makuch, Sebastian Agrawal, Siddarth |
author_sort | Woźniak, Marta |
collection | PubMed |
description | Gynecological cancer confers an enormous burden among women worldwide. Accumulating evidence points to the role of phytochemicals in preventing cervical, endometrial, and ovarian cancer. Experimental studies emphasize the chemopreventive and therapeutic potential of plant-derived substances by inhibiting the early stages of carcinogenesis or improving the efficacy of traditional chemotherapeutic agents. Moreover, a number of epidemiological studies have investigated associations between a plant-based diet and cancer risk. This literature review summarizes the current knowledge on the phytochemicals with proven antitumor activity, emphasizing their effectiveness and mechanism of action in gynecological cancer. |
format | Online Article Text |
id | pubmed-7865323 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-78653232021-02-07 Phytochemicals in Gynecological Cancer Prevention Woźniak, Marta Krajewski, Rafał Makuch, Sebastian Agrawal, Siddarth Int J Mol Sci Review Gynecological cancer confers an enormous burden among women worldwide. Accumulating evidence points to the role of phytochemicals in preventing cervical, endometrial, and ovarian cancer. Experimental studies emphasize the chemopreventive and therapeutic potential of plant-derived substances by inhibiting the early stages of carcinogenesis or improving the efficacy of traditional chemotherapeutic agents. Moreover, a number of epidemiological studies have investigated associations between a plant-based diet and cancer risk. This literature review summarizes the current knowledge on the phytochemicals with proven antitumor activity, emphasizing their effectiveness and mechanism of action in gynecological cancer. MDPI 2021-01-26 /pmc/articles/PMC7865323/ /pubmed/33530651 http://dx.doi.org/10.3390/ijms22031219 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Woźniak, Marta Krajewski, Rafał Makuch, Sebastian Agrawal, Siddarth Phytochemicals in Gynecological Cancer Prevention |
title | Phytochemicals in Gynecological Cancer Prevention |
title_full | Phytochemicals in Gynecological Cancer Prevention |
title_fullStr | Phytochemicals in Gynecological Cancer Prevention |
title_full_unstemmed | Phytochemicals in Gynecological Cancer Prevention |
title_short | Phytochemicals in Gynecological Cancer Prevention |
title_sort | phytochemicals in gynecological cancer prevention |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865323/ https://www.ncbi.nlm.nih.gov/pubmed/33530651 http://dx.doi.org/10.3390/ijms22031219 |
work_keys_str_mv | AT wozniakmarta phytochemicalsingynecologicalcancerprevention AT krajewskirafał phytochemicalsingynecologicalcancerprevention AT makuchsebastian phytochemicalsingynecologicalcancerprevention AT agrawalsiddarth phytochemicalsingynecologicalcancerprevention |