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Bscl2 Deficiency Does Not Directly Impair the Innate Immune Response in a Murine Model of Generalized Lipodystrophy
Congenital Generalized Lipodystrophy type 2 (CGL2) is the most severe form of lipodystrophy and is caused by mutations in the BSCL2 gene. Affected patients exhibit a near complete lack of adipose tissue and suffer severe metabolic disease. A recent study identified infection as a major cause of deat...
Autores principales: | Roumane, Ahlima, Mcilroy, George D., Balci, Arda, Han, Weiping, Delibegović, Mirela, Baldassarre, Massimiliano, Newsholme, Philip, Rochford, Justin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865406/ https://www.ncbi.nlm.nih.gov/pubmed/33498782 http://dx.doi.org/10.3390/jcm10030441 |
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