Cargando…

TGF-β in Cancer: Metabolic Driver of the Tolerogenic Crosstalk in the Tumor Microenvironment

SIMPLE SUMMARY: Metabolic reprogramming is an emerging hallmark in cancer. Beside the malignant compartment, the tumor microenvironment also undergoes to a metabolic skewing, contributing to the neoplastic progression and metastasizing process. Growing evidence pointed out a central role for Transfo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Angioni, Roberta, Sánchez-Rodríguez, Ricardo, Viola, Antonella, Molon, Barbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865468/ https://www.ncbi.nlm.nih.gov/pubmed/33499083 http://dx.doi.org/10.3390/cancers13030401

Ejemplares similares

TGF-β Mediated Crosstalk Between Malignant Hepatocyte and Tumor Microenvironment in Hepatocellular Carcinoma
por: Gupta, Devendra Kumar, et al.
Publicado: (2014)

IL1β Promotes TMPRSS2 Expression and SARS-CoV-2 Cell Entry Through the p38 MAPK-GATA2 Axis
por: Cioccarelli, Chiara, et al.
Publicado: (2021)

A key driver to promote HCC: Cellular crosstalk in tumor microenvironment
por: Liu, Pengyue, et al.
Publicado: (2023)

TGF-β signaling in the tumor metabolic microenvironment and targeted therapies
por: Shi, Xueke, et al.
Publicado: (2022)

TGF-β Suppresses β-Catenin-Dependent Tolerogenic Activation Program in Dendritic Cells
por: Vander Lugt, Bryan, et al.
Publicado: (2011)

Metabolic Cancer-Macrophage Crosstalk in the Tumor Microenvironment
por: de Goede, Kyra E., et al.
Publicado: (2020)

COVID-19 Vaccination Limits Systemic Danger Signals in SARS-CoV-2 Infected Patients
por: Angioni, Roberta, et al.
Publicado: (2022)

GM-CSF Nitration Is a New Driver of Myeloid Suppressor Cell Activity in Tumors
por: Calì, Bianca, et al.
Publicado: (2021)

Psoriasis and Cardiovascular Diseases: An Immune-Mediated Cross Talk?
por: Orlando, Gloria, et al.
Publicado: (2022)

Inducing a tolerogenic microenvironment within tissues
por: Cobbold, Stephen P
Publicado: (2011)

TGFβ Signaling in the Pancreatic Tumor Microenvironment
por: Principe, Daniel R., et al.
Publicado: (2021)

TGFβ and the Tumor Microenvironment in Colorectal Cancer
por: Waldner, Maximilian J., et al.
Publicado: (2023)

Metabolic Plasticity of Melanoma Cells and Their Crosstalk With Tumor Microenvironment
por: Avagliano, Angelica, et al.
Publicado: (2020)

T Cells and Cancer: How Metabolism Shapes Immunity
por: Molon, Barbara, et al.
Publicado: (2016)

Synthetic TGF-β Signaling Agonist-Treated Dendritic Cells Induce Tolerogenicity and Antirheumatic Effects
por: Oh, Ji-Soo, et al.
Publicado: (2022)

Chemokines and Chemokine Receptors: Orchestrating Tumor Metastasization
por: Marcuzzi, Elisabetta, et al.
Publicado: (2018)

Metabolic regulatory crosstalk between tumor microenvironment and tumor-associated macrophages
por: Chen, Degao, et al.
Publicado: (2021)

The role of TGF-β in the tumor microenvironment of pancreatic cancer
por: Luo, Qiang, et al.
Publicado: (2022)

Crosstalk between Macrophages, T Cells, and Iron Metabolism in Tumor Microenvironment
por: Shen, Lesang, et al.
Publicado: (2021)

Smoothing T cell roads to the tumor: Chemokine post-translational regulation
por: Molon, Barbara, et al.
Publicado: (2012)

Intercellular Calcium Signaling Induced by ATP Potentiates Macrophage Phagocytosis
por: Zumerle, Sara, et al.
Publicado: (2019)

Age-severity matched cytokine profiling reveals specific signatures in Covid-19 patients
por: Angioni, Roberta, et al.
Publicado: (2020)

TGF-β Signaling: From Tissue Fibrosis to Tumor Microenvironment
por: Chung, Jeff Yat-Fai, et al.
Publicado: (2021)

Crosstalk between p53 and TGF-β Signalling
por: Elston, Rebecca, et al.
Publicado: (2012)

Correction: Marcuzzi, E., et al. Chemokines and Chemokine Receptors: Orchestrating Tumor Metastasization. Int. J. Mol. Sci. 2019, 20, 96
por: Marcuzzi, Elisabetta, et al.
Publicado: (2019)

Editorial: Cancer metabolism: molecular insights, metabolic crosstalk in the tumor microenvironment, and implications for therapy
por: Chaube, Balkrishna, et al.
Publicado: (2023)

Metabolic reprogramming and crosstalk of cancer-related fibroblasts and immune cells in the tumor microenvironment
por: Zhu, Yifei, et al.
Publicado: (2022)

Tolerogenic Properties of Lymphatic Endothelial Cells Are Controlled by the Lymph Node Microenvironment
por: Cohen, Jarish N., et al.
Publicado: (2014)

Role of TGFβ in regulation of the tumor microenvironment and drug delivery (Review)
por: PAPAGEORGIS, PANAGIOTIS, et al.
Publicado: (2015)

Pathway crosstalk enables cells to interpret TGF-β duration
por: Zhang, Jingyu, et al.
Publicado: (2018)

At the Crux of Joint Crosstalk: TGFβ Signaling in the Synovial Joint
por: Bailey, Karsyn N., et al.
Publicado: (2022)

Silencing of TGF-β1 in tumor cells impacts MMP-9 in tumor microenvironment
por: Moore-Smith, Lakisha D., et al.
Publicado: (2017)

Metabolic Reprogramming of Thyroid Cancer Cells and Crosstalk in Their Microenvironment
por: Bao, Lisha, et al.
Publicado: (2021)

Metabolism Is Central to Tolerogenic Dendritic Cell Function
por: Sim, Wen Jing, et al.
Publicado: (2016)

Crosstalk between arginine, glutamine, and the branched chain amino acid metabolism in the tumor microenvironment
por: Wetzel, Tanner J., et al.
Publicado: (2023)

Nutrient Sensing via mTOR in T Cells Maintains a Tolerogenic Microenvironment
por: Howie, Duncan, et al.
Publicado: (2014)

Roles of ubiquitination in the crosstalk between tumors and the tumor microenvironment (Review)
por: Zhang, Xiuzhen, et al.
Publicado: (2022)

Low Dose Cyclophosphamide Modulates Tumor Microenvironment by TGF-β Signaling Pathway
por: Zhong, Hui, et al.
Publicado: (2020)

An oncolytic virus–delivered TGFβ inhibitor overcomes the immunosuppressive tumor microenvironment
por: DePeaux, Kristin, et al.
Publicado: (2023)

Signaling crosstalk between TGFβ and Dishevelled/Par1b
por: Mamidi, A, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_iiornmfei4g5jkknqt3cgba1fa