Cargando…

Kahweol, a Diterpenoid Molecule, Inhibits CTGF-Dependent Synthetic Phenotype Switching and Migration in Vascular Smooth Muscle Cells

Vascular smooth muscle cell (VSMC) phenotype switching from contractile to synthetic is essential for proliferation and migration in vascular pathophysiology. Connective tissue growth factor (CTGF) is a matricellular protein involved in cell adhesion, migration, and proliferation. Kahweol, a diterpe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Jeong Hee, Choi, Seok Tae, Kang, Young Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865488/ https://www.ncbi.nlm.nih.gov/pubmed/33530626 http://dx.doi.org/10.3390/molecules26030640

Ejemplares similares

Targeting smooth muscle cell phenotypic switching in vascular disease
por: Chakraborty, Raja, et al.
Publicado: (2021)

Role of Vascular Smooth Muscle Cell Phenotype Switching in Arteriogenesis
por: Ashraf, Jasni Viralippurath, et al.
Publicado: (2021)

Vascular smooth muscle cell phenotype switching in carotid atherosclerosis
por: Chou, Elizabeth L., et al.
Publicado: (2021)

Vascular Smooth Muscle Cells Phenotypic Switching in Cardiovascular Diseases
por: Tang, Hao-Yue, et al.
Publicado: (2022)

How vascular smooth muscle cell phenotype switching contributes to vascular disease
por: Cao, Genmao, et al.
Publicado: (2022)

SRF SUMOylation modulates smooth muscle phenotypic switch and vascular remodeling
por: Xu, Yue, et al.
Publicado: (2023)

Lactate promotes vascular smooth muscle cell switch to a synthetic phenotype by inhibiting miR-23b expression
por: Hu, Yanchao, et al.
Publicado: (2022)

Palmitic acid inhibits vascular smooth muscle cell switch to synthetic phenotype via upregulation of miR-22 expression
por: Hu, Yanchao, et al.
Publicado: (2022)

Reactive Oxygen Species: Modulators of Phenotypic Switch of Vascular Smooth Muscle Cells
por: Badran, Adnan, et al.
Publicado: (2020)

Guidance Molecules in Vascular Smooth Muscle
por: Finney, Alexandra Christine, et al.
Publicado: (2018)

Loss of the Mechanotransducer Zyxin Promotes a Synthetic Phenotype of Vascular Smooth Muscle Cells
por: Ghosh, Subhajit, et al.
Publicado: (2015)

Inducing Energetic Switching Using Klotho Improves Vascular Smooth Muscle Cell Phenotype
por: Docherty, Craig K., et al.
Publicado: (2021)

Pressure and stiffness sensing together regulate vascular smooth muscle cell phenotype switching
por: Swiatlowska, Pamela, et al.
Publicado: (2022)

Integrin α9 regulates smooth muscle cell phenotype switching and vascular remodeling
por: Jain, Manish, et al.
Publicado: (2021)

Notch signaling regulates strain-mediated phenotypic switching of vascular smooth muscle cells
por: Karakaya, Cansu, et al.
Publicado: (2022)

Bindarit Inhibits Human Coronary Artery Smooth Muscle Cell Proliferation, Migration and Phenotypic Switching
por: Maddaluno, Marcella, et al.
Publicado: (2012)

Therapeutic MK2 inhibition blocks pathological vascular smooth muscle cell phenotype switch
por: Tierney, J. William, et al.
Publicado: (2021)

NLRP3 Inflammasome Activation Controls Vascular Smooth Muscle Cells Phenotypic Switch in Atherosclerosis
por: Burger, Fabienne, et al.
Publicado: (2021)

Smooth Muscle–Selective Inhibition of Nuclear Factor‐κB Attenuates Smooth Muscle Phenotypic Switching and Neointima Formation Following Vascular Injury
por: Yoshida, Tadashi, et al.
Publicado: (2013)

Cafestol and Kahweol: A Review on Their Bioactivities and Pharmacological Properties
por: Ren, Yaqi, et al.
Publicado: (2019)

Recent Updates on the Functional Impact of Kahweol and Cafestol on Cancer
por: Eldesouki, Salma, et al.
Publicado: (2022)

Cathelicidin Modulates Vascular Smooth Muscle Cell Phenotypic Switching through ROS/IL-6 Pathway
por: Dong, Xiaoliang, et al.
Publicado: (2020)

The GEF Cytohesin-2/ARNO Mediates Resistin induced Phenotypic Switching in Vascular Smooth Muscle Cells
por: Heun, Yvonn, et al.
Publicado: (2020)

MiR-9 promotes the phenotypic switch of vascular smooth muscle cells by targeting KLF5
por: LU, Xiaochun, et al.
Publicado: (2019)

Insulin Resistance Promotes the Formation of Aortic Dissection by Inducing the Phenotypic Switch of Vascular Smooth Muscle Cells
por: Zheng, Hui, et al.
Publicado: (2022)

Inhibition of CDK9 attenuates atherosclerosis by inhibiting inflammation and phenotypic switching of vascular smooth muscle cells
por: Huang, Shushi, et al.
Publicado: (2021)

Induction of ferroptosis promotes vascular smooth muscle cell phenotypic switching and aggravates neointimal hyperplasia in mice
por: Zhang, Shunchi, et al.
Publicado: (2022)

KLF4-PFKFB3-driven glycolysis is essential for phenotypic switching of vascular smooth muscle cells
por: Zhang, Xinhua, et al.
Publicado: (2022)

Crosstalk between BMP signaling and KCNK3 in phenotypic switching of pulmonary vascular smooth muscle cells
por: Yeo, Yeongju, et al.
Publicado: (2022)

Targeting the Crosstalk of Immune Response and Vascular Smooth Muscle Cells Phenotype Switch for Arteriovenous Fistula Maturation
por: Rai, Vikrant, et al.
Publicado: (2022)

Methyltransferase‐like 3 suppresses phenotypic switching of vascular smooth muscle cells by activating autophagosome formation
por: Fang, Ze‐Min, et al.
Publicado: (2022)

Emerging regulators of vascular smooth muscle cell migration
por: Afewerki, TecLino, et al.
Publicado: (2019)

Synthetic study toward the diterpenoid aberrarone
por: Shi, Liang, et al.
Publicado: (2022)

MALT1 accelerates proatherogenic vascular smooth muscle cell growth, invasion and synthetic phenotype switching via nuclear factor‑κB signaling‑dependent way
por: Zheng, Haiying, et al.
Publicado: (2023)

TXNIP Suppresses the Osteochondrogenic Switch of Vascular Smooth Muscle Cells in Atherosclerosis
por: Woo, Sang-Ho, et al.
Publicado: (2022)

Panax notoginseng Saponins Attenuate Phenotype Switching of Vascular Smooth Muscle Cells Induced by Notch3 Silencing
por: Liu, Nan, et al.
Publicado: (2015)

Interleukin-11 is important for vascular smooth muscle phenotypic switching and aortic inflammation, fibrosis and remodeling in mouse models
por: Lim, Wei-Wen, et al.
Publicado: (2020)

Apatinib attenuates phenotypic switching of arterial smooth muscle cells in vascular remodelling by targeting the PDGF Receptor‐β
por: Shao, Wenchao, et al.
Publicado: (2020)

GPR30 Promotes the Phenotypic Switching of Vascular Smooth Muscle Cells via Activating the AKT and ERK Pathways
por: Zha, Binshan, et al.
Publicado: (2020)

Epigenetic Regulation of Vascular Smooth Muscle Cell Phenotype Switching in Atherosclerotic Artery Remodeling: A Mini-Review
por: Zurek, Michelle, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ckb9977m3ui97p2ehsf94er2r5