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Protease-Specific Biomarkers to Analyse Protease Inhibitors for Emphysema Associated with Alpha 1-Antitrypsin Deficiency. An Overview of Current Approaches

As a known genetic cause of chronic obstructive pulmonary disease (COPD), alpha1-antitrypsin deficiency (AATD) can cause severe respiratory problems at a relatively young age. These problems are caused by decreased or absent levels of alpha1-antitrypsin (AAT), an antiprotease which is primarily func...

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Detalles Bibliográficos
Autores principales: Viglio, Simona, Bak, Elisabeth G., Schouten, Iris G. M., Iadarola, Paolo, Stolk, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865489/
https://www.ncbi.nlm.nih.gov/pubmed/33494436
http://dx.doi.org/10.3390/ijms22031065