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Human iPSC-Based Modeling of Central Nerve System Disorders for Drug Discovery

A high-throughput drug screen identifies potentially promising therapeutics for clinical trials. However, limitations that persist in current disease modeling with limited physiological relevancy of human patients skew drug responses, hamper translation of clinical efficacy, and contribute to high c...

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Detalles Bibliográficos
Autores principales:	Qian, Lu, TCW, Julia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865494/ https://www.ncbi.nlm.nih.gov/pubmed/33530458 http://dx.doi.org/10.3390/ijms22031203

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