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The Interactions of DNA Repair, Telomere Homeostasis, and p53 Mutational Status in Solid Cancers: Risk, Prognosis, and Prediction

SIMPLE SUMMARY: p53 is a nuclear transcription factor with a pro-apoptotic function. Somatic mutations in this gene represent one of the most critical events in human carcinogenesis. The disruption of genomic integrity due to the accumulation of various kinds of DNA damage, deficient DNA repair capa...

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Detalles Bibliográficos
Autores principales:	Vodicka, Pavel, Andera, Ladislav, Opattova, Alena, Vodickova, Ludmila
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865496/ https://www.ncbi.nlm.nih.gov/pubmed/33513745 http://dx.doi.org/10.3390/cancers13030479

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