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Targeting Lysyl Oxidase Family Meditated Matrix Cross-Linking as an Anti-Stromal Therapy in Solid Tumours

SIMPLE SUMMARY: To improve efficacy of solid cancer treatment, efforts have shifted towards targeting both the cancer cells and the surrounding tumour tissue they grow in. The lysyl oxidase (LOX) family of enzymes underpin the fibrotic remodeling of the tumour microenvironment to promote both cancer...

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Detalles Bibliográficos
Autores principales:	Setargew, Yordanos F.I., Wyllie, Kaitlin, Grant, Rhiannon D., Chitty, Jessica L., Cox, Thomas R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865543/ https://www.ncbi.nlm.nih.gov/pubmed/33513979 http://dx.doi.org/10.3390/cancers13030491

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